Got SC2, but didn't really get into it, never even finished the single player campaign. The RTS genre somehow doesn't appeal to me so much, I never finished the original SC or WC3 either.
The Witcher 2 is great, looks awesome and just plays great. Combat is challenging: it's rather difficult without feeling truely impossible. It also is and isn't like the first Witcher game: combat is different now (left click for fast swing, right click for slow swing, double tap movement keys to roll away, ...), but the whole atmosphere is still the same, it's still a dark & rather adult game.
Apart from SW:TOR & The Secret World there's no MMO's that appeal to me.
Duke Nukem Forever on the one hand looks like some fun over-the-top action (at least when watching the trailer), but I'm not sure I want to pay full price for it.
Have to get Infamous 2 still as I liked the first game, also Portal 2 (for the PS3 as it included the PC version iirc) and was contemplating LA Noire. Too many games, too little time! New Deus Ex title is also out in August + Uncharted 3 and Batman: Arkham City are also due this year.