Thanks for the link Sax. Game arrived today, just spent a few hours exploring and getting out of the starter area. Impressed so far. I've run into one nasty bug though, get a permanent black screen during NPC interaction sometimes. Only get it with HDR turned on. Seems from forums others have had the same problem with Nvidia cards (got a 6800GT her, latest drivers).
Will give the tweaks a try. The FOV to 90 (from 75) would be a good one (easier on my eyes) if the menus worked in 90 degree view. Sadly they don't at the moment, maybe they'll patch it.